FC Barcelona hammered Newcastle United F.C. 7-2 to reach the Champions League quarter-finals, while Liverpool F.C., Bayern Munich and Atltico Madrid also advanced.
Chelsea battled from two goals down to beat West Ham 3-2 in the Premier League on Saturday with a stoppage-time Enzo Fernandez winner.
Second-string Liverpool were thumped 3-0 by Crystal Palace as Ismaila Sarr struck twice for the visitors in the League Cup on Wednesday, booking the London side's spot in the quarter-finals and piling more misery on Arne Slot's struggling side.
Arsenal missed a chance to tighten their grip on the Premier League title race with a 1-1 draw at 10-man Chelsea on Sunday.
Premier League leaders Liverpool needed Trent Alexander-Arnold's second-half equaliser to secure a 2-2 draw at Aston Villa on Wednesday that lifted them eight points clear at the top.
Manchester United manager Ruben Amorim would have enjoyed some relative calm during the international break after backing from club co-owner Jim Ratcliffe but will find himself in the Premier League maelstrom once again at Liverpool on Sunday.
Premier League leaders Arsenal needed two own goals, the second deep in stoppage time, to scrape a 2-1 home win over bottom club Wolverhampton Wanderers and open a five-point gap, while earlier on Saturday Mohamed Salah put aside a tumultuous week to help Liverpool beat Brighton and Hove Albion 2-0.
Liverpool roared back from a goal behind to thrash Tottenham Hotspur 5-1 and wrap up the English Premier League title in style.
IMAGES from UEFA Champions League matches played on Wednesday
Virgil van Dijk scored with a stunning late header in the second minute of stoppage time to give Liverpool a 3-2 victory over Atletico Madrid in their opening group stage match of the Champions League, at Anfield, on Wednesday.
Liverpool talisman Mo Salah and substitute Federico Chiesa struck late goals as the Premier League champions began the defence of their title by beating Bournemouth 4-2 in a thriller on the opening night of the season at Anfield on Friday.
Crystal Palace beat Premier League champions Liverpool 3-2 on penalties to win the Community Shield after an entertaining 2-2 draw at Wembley on Sunday.
Reigning Premier League champions Liverpool honour Portugal forward Diogo Jota, who died in a car crash alongside his brother Andre Silva last month, ahead of the season-opener kick-off against Bournemouth on Friday.
Arsenal maintained a searing pace at the top of the Premier League with a straightforward 2-0 win at Burnley, while Liverpool snapped a dreadful four-match losing run with a 2-0 victory over Aston Villa to climb provisionally to third.
Liverpool's Salah named Premier League player of the season, Gravenberch best youngster
Liverpool's Dominik Szoboszlai struck the first telling blow in the Premier League title race with a dazzling free kick late on giving his side a 1-0 victory over rivals Arsenal.
IMAGES from the Premier League matches played on Sunday
Goals from Pedro Neto and Enzo Fernandez earned Chelsea a 2-0 victory at lowly Burnley on Saturday, a win that moved the Blues within three points of Premier League leaders Arsenal.
IMAGES from the EPL matches played on Saturday
Fresh off a dominant title-winning campaign, Liverpool kick off the new Premier League season on Friday as the team to beat, as the Reds have transitioned from Juergen Klopp's high-octane chaos to a more measured possession-based style under Arne Slot.
Liverpool end victorious season with 1-1 draw with Crystal Palace
The 22-year-old German is Liverpool's most-expensive signing ever, ahead of captain Virgil van Dijk who joined for 75 million pounds in 2017.
After Saturday's 2-1 win at Chelsea - their 12th in 13 league matches - Aston Villa have claimed 18 points from losing positions so far this season, more than any other team.
'If you were to lift the two trophies, I think you have a pretty good chance to be on a nice list of captains that have achieved great things in this club.'
Liverpool continued their march towards the Premier League title with a 1-0 victory over Everton in a scrappy Merseyside derby as Diogo Jota slotted home the winner in the second half on Wednesday.
Champions Liverpool edged Newcastle United 3-2 in a thrilling finish thanks to a stoppage-time winner by teenaged Premier League debutant Rio Ngumoha.
Bayern Munich made it 16 wins from 16 games this season to underline their credentials as early Champions League favourites, beating holders Paris St Germain 2-1 away as Luis Diaz scored two goals and was shown a red card on Tuesday.
Images from Premier League matches played on Sunday.
IMAGES from the UEFA Champions League matches played on Wednesday
Winning back-to-back titles for the first time since 1984 is likely to prove a rather more arduous challenge for Liverpool.
A much-changed Liverpool were dumped out of the FA Cup by struggling second-tier side Plymouth Argyle, who pulled off a stunning 1-0 fourth round win.
A wake is expected to take place at a chapel in Gondomar from 4 PM (1500 GMT) and a funeral on Saturday at a church nearby at 10 AM local time, Gondomar's mayor's office said.
'I was desperate for them (the fan to be here) of course, for all the fans around the world, for the fans here, but for us as well.'
Liverpool shrugged off the absence of Mohamed Salah as midfielder Dominik Szoboszlai scored an 88th-minute penalty to give them a 1-0 Champions League win at Inter Milan.
With 12 games remaining Manchester City are in fourth place with 44 points, just five ahead of 10th-placed Fulham.
Real Madrid will play local rivals Atletico Madrid while Bayern Munich were drawn against Bundesliga title challengers Bayer Leverkusen on Friday.
Liverpool took another step towards the Premier League title with a 2-0 win at Manchester City.
Tottenham have not won any silverware since they beat Chelsea in the 2008 League Cup final.
Lucas Bergvall scored his first goal for Tottenham Hotspur to give his side a surprise 1-0 victory over holders Liverpool in the first leg of their League Cup semi-final on Wednesday.
Former Liverpool manager Juergen Klopp said he has no immediate plans to return to management.